What causes anteromedial rotatory instability?
Anteromedial rotatory instability is usually the result of an injury with damage to several structures:
It is one of the multiligament injuries of the knee.
"....While most [medial collateral ligament (MCL)] injuries can be treated nonoperatively, medial instability may remain, particularly with higher-grade injuries. Residual MCL laxity can impair knee function, cause chronic pain, and lead to higher rates of ACL reconstruction failure...."
Other relevant links -
Medial collateral ligament, Medial meniscus, Anterior cruciate ligament, Posterior oblique ligament