Chondroitin

Written by Dr Sheila Strover on March 14, 2025

Chondroitin (chondroitin sulphate) is a chemical substance which is widely taken by arthritics to slow joint cartilage breakdown. Page updated January 2024 by Dr Sheila Strover (Clinical Editor)

chondroitin for arthritis

Chondroitin sulphate is a supplement used for arthritis

Where does chondroitin sulphate come from?

Chondroitin sulphate is extracted mostly from shellfish, and is a component of normal cartilage, helping to give it its elasticity.

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How does chondroitin sulphate affect arthritis?

It appears that this supplement affects arthritis in various ways - reducing inflammation, slowing joint breakdown, stabilising cells from breakdown and neutralising free radicals.

"CS [Chondroitin Sulphate] is part of the Osteoarthritis Research Society International (OARSI) recommendations for the management of knee OA [Osteoarthritis] and of the European League Against Rheumatism (EULAR) recommendations for the management hip and knee OA....[It] plays a major role in allowing cartilage to resist pressure stresses during various loading conditions....[despite] its efficacy [still being] under debate...."

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