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Author Topic: Synvisic one adverse reactions untold by dr's  (Read 3659 times)

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Offline SoSher

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Synvisic one adverse reactions untold by dr's
« on: July 10, 2014, 08:09:53 AM »
I'm a 46yo female with osteo arthritis in both knees now started after skateboarding accident 30 years ago.2 Or surg trips scope & lig transfer.I have pain swelling, weakness popping, clicking, grinding & locking up.Now have problems with all dreaded stairs.
I had 3 inj sessions in both knees every 6 months. My injections done by pain management specialist under floroiscope xray with local anesthetic 5% lidocaine solution than dye injected to find exact place for synvisic inj. No pain  during procedure add a bandaid and home within 1 hour. No pain with 1st injections 2 injections go alot of swelling stiffness pain and difficulty walking for about 10 days.
My 3 set of bi lat knee injections was a extreme reaction in both knees less than 5 hour post inj. Pain & swelling so extreme called the on call physician to report my problem. Its to soon for infection but drug reports state if some gel leaks into surrounding tissue there is mild reactions noted by other patients. My doctor did inform me due last reaction I may experience a worst reaction. Which happened. I believe the literature on synvisic does report adverse reactions but Dr's aren't always forthcoming with that information. Now I'm at a crossroads do grin chance another bad pain reaction that last 20+ day for the later 6 months benefit or try one of the other synvisic type drugs available.I won't do both knee at the same time. If you get a reactions try benadryl it might help & doesn't hurt. But reactions are noted and aren't that rare might not be an actual allergic reaction but its real and hideous for those going through it.

Offline MDAL

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Re: Synvisic one adverse reactions untold by dr's
« Reply #1 on: July 10, 2014, 10:33:53 PM »

I have a lot of experience in taking injection, lost count of the PRP, Hyaluronic Acid, Stem cells, etc...

What you are describing to me, I had to read it with an open mouth, because it is really beyond belief... I have never heard of such thing, as ultra-sound guided injection (with dye) to the injury spot of Hyaluronic Acid... this one is unheard of to me...

The all point of HA, is to fill the joint with a viscous substance similar to what you already have in there (add lubricating oil), in order to reduce friction. No matter where you inject it, it will always float around freely. I don't see what difference does it make where exactly you drop it, since the joint has no barriers.

In my experience with injections, bad reactions are directly proportional to the amount of trauma caused by the needle. The more the doctor spends messing around, the more days it will take to recover from it, the more will be the inflammatory reaction. If he is "exploring" the knee with the typical big needle of HA, he will pierce cartilage all over the place, causing more damage while over-traumatizing the injection entry point, etc.

The cells damaged by the needle release proteins with stress signals, that raise an inflammatory reaction, same thing it happens if you decide to perfurate a muscle all over the place with a huge needle. From so much messing around there could also be internal bleeding in the injection poin, raising even more inflammation.

Typically HA injections are done by the easiest entry point, just dropping the fluid into the synovial capsule with steady needle and it is meant to be done with the minimal damage possible. The point is just to fill up, the HA will spread around on it's own, it's just a oil. It doesn't matter where you put it in the first place.

I don't think what you had was a side effect of the Synvisc... it seems to be a side effect of a doctor who either is not 100% in tune with the concept of common sense, or decided to charge some extra bucks for his high tech laser guided missile injection of "oil" to impress...

Injections in the way you described are used for stem cell treatments, and even those there is no real evidence that on spot delivery will make any difference compared to random delivery into the joint space, since it's a fluid and it will melt anyway with the remaining fluid in the joint.

My previous injections of HA, were without anesthesia, they did hurt, but the injection lasted 3 seconds and it was over... As a matter of fact, if you take the injection from a relaxed position and relaxed muscles, and the doctor is capable of holding the needle straight the pain is not even that bad... what hurts is when you feel the needle motion.

I am just telling you my opinion... but I am a bit suspicious of the motives of that doctor to put up that tech show... not sure if they are in your best interest... apparently not...