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Author Topic: Hyalgan  (Read 11646 times)

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Offline Argie

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Hyalgan
« on: October 23, 2003, 04:43:58 AM »
I had an MRI and was diagnosed with severe chondromalacia.

My OS suggested Arthroscopy or an injection of Hyalgan for starters.

Has anyone heard of anyone having had this injection. From what I have read, this is similar to Synvisc but requires 5 injections as opposed to Synvisc.
|==>--

Offline panbagnat

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Re: Hyalgan
« Reply #1 on: October 23, 2003, 01:50:23 PM »
Hi,

I had a LR on my right knee last June but before that they tried 3 injections of Ostenil and it did not do anything.  However, 2 weeks ago (4 months after the LR), I had an injection of DUROLANE: it is a new product, with a concentration higher than SYNVISC and you only need 1 injection.  It did not remove all the pain I have, but I can say I can see a very little improvement.  Actually it is supposed to take 4 weeks before beeing completely operational, so we'll see.

By the way sorry by adavance for my very bad spelling....

Offline Leentje

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Re: Hyalgan
« Reply #2 on: October 23, 2003, 10:26:52 PM »
Hi

Synvisc is a product name, the fluid they inject is Hyaluronic acid. I had 2 series of 3 injections : 1 series in august 2001 with Ostenil and 1 series spetember 2003 with Adant. These are product names U probably haven't heard off (they are often used here in Belgium) but it's the same thing as Synvisc.

I didn't have much painrelief from the 1st series, now I am almost painfree! But this is only a temporary effect, it will ware off in a few months and I will probably need more serie in future. But for now I am glad it works. But if I squat standing only on my bad L knee (had a TTT), U can hear a lot of cracking and crunching, people just can't understand that it doesn't hurt a lot :P

Good luck!
Bilat patellar malalignment/PFdysplasia
00/06/83 L wrist #
11/12/00 L knee LR + chondroplasty
21/08/02 L knee TTT
02/03/04 L knee stretched PCL
11/09/07 L ankle dislocation/medial avulsion #
25/05/09 L ankle medial avulsion # AGAIN!
05/06/13 R ankle dislocation

Offline seegalone

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Re: Hyalgan
« Reply #3 on: January 14, 2004, 02:11:59 AM »
Hello everyone,
I'm new here. I live in the States, how is that for reaching out...
I have ostheoarhritis in the R knee, post arthroscopy about 18 years ago (skiing injury). I'm a bit confused (which could be my normal state of mind anyway ;)) about different products for injections. Am I correct that the newest is hyaluronan, under perhaps different brand names, in the States it's Hylan G-F 20 which has a double molecular weght of 20 as opposed to 10 in the past. It was approved here sometimes in the fall, but I'm quite sure that it was available in Europe for much longer.
I am trying to learn all I can here about the efficacy of these injections. The pain i have usually comes on after walking for 2-3 blocks and gets rather bad, however rest usually relieves it. I have not even found  an OS yet, as I do not care much for the one who was taking care of me before. The odds of finding a OS in Chicago at this Forum are probably nill, but it does not hurt to mention it...
Krys

Offline squan36

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Re: Hyalgan
« Reply #4 on: January 30, 2004, 11:47:03 PM »
Hi, I'm new here too !!!

I have an incredibly loud squishing noise coming from my right knee. Xrays have revealed some arthritis but, to me it sounds like much more. I can't find any info on this "squishing" noise coming from my knee.

Anyway, I take Celebrex 2x daily (it really doesn't do anything) and received the series of 5 Hyalgen injections in September. They have done nothing !

The noise is getting louder and the dull pain around the kneecap is getting stronger. I have general weakness in that knee when walking and the noise can only be heard when walking UP stairs.

The injections themselves were not too painful just uncomfortable. Like I said however, they have not provided any relief. I'm beginning to wonder if this is something more than arthritis...

Good Luck !
Brian

Offline JorJor

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Re: Hyalgan
« Reply #5 on: January 31, 2004, 12:52:11 AM »
I am in the middle of getting my 7th series of injections. I have tried all the lubricate injections products on the US market and found Hyalgan works the best for me. To me it is worth a try before being cut on...
5 surgeries (2 Micro-Fractures)! 8 rounds of Synvisc, Hylogan(sp?) & Supartz.  5th Scope 2/13/03 chrondoplasty & rp m. meniscus. Won't let it stop me...walked 60 miles in 3 Days for Breast Cancer.

Offline seegalone

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Re: Hyalgan
« Reply #6 on: February 06, 2004, 09:14:56 AM »
Hi, Brian,
Just my 2c. From my own experience- my first OS took a couple of Xrays,  did not suggest an MRI, and did not think the problem in my knee was severe enough to warrant any intervention. I finally saw someone else, who sent me for a high quality MRI (apperently they are not all the same, high spin echo something...) and it turns out that there is a lot more to the details of the OA in my knee that it was originally presumed. I thought maybe you should ask your doc about it, or go for a second opinion...
Good luck.
Krys

Offline squan36

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Re: Hyalgan
« Reply #7 on: February 08, 2004, 02:28:05 AM »
Thanks Krys ! I will be getting a second opinion...

Offline Abbie s Mom

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Re: Hyalgan
« Reply #8 on: September 16, 2004, 05:50:59 PM »
Just a warning, I have no allergies to eggs, poultry, and sleep with a down pillow. One day after injection knee swelled a bit, then slowly my temperature rose to 104.7 C. I hear I am one of the only people with such a reaction in the US, but it's something to think of. I was in pain before, but now it's worse and I am 29 with a walker.

Jenn
Jennifer Reilly
Abigael's mom 12/4/02
** No problems prior to fall of 12/7/03 on black ice. Is this related??? hmmmm....
Current diagnosis:
Bilateral Femoral-Patella Chrondo
PFS
Mal-tracking

Offline grannynan

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Re: Hyalgan
« Reply #9 on: September 16, 2004, 07:12:46 PM »
Hi, Jenn:
How long ago did you have your injection?  Is it back to it's pre-injection condition?  I had 2 and had a bad reaction to both of them, so have aborted the treatment.  I did not get a fever, but my knee swelled to twice it's normal swollen size and was extremely painful.  My knee still feels considerably worse than it did prior to the first treatment back in August.
Nancy.

Offline Abbie s Mom

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Re: Hyalgan
« Reply #10 on: September 16, 2004, 08:55:26 PM »
I had only the first injection. Now the doctor wants to try Synvisc. I don't want any injections further!
Jennifer Reilly
Abigael's mom 12/4/02
** No problems prior to fall of 12/7/03 on black ice. Is this related??? hmmmm....
Current diagnosis:
Bilateral Femoral-Patella Chrondo
PFS
Mal-tracking

Offline grannynan

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Re: Hyalgan
« Reply #11 on: September 16, 2004, 09:37:39 PM »
I actually had Synvisc, not hylagan.  I don't want any more either!!!!

Offline wend1175

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Re: Hyalgan
« Reply #12 on: September 19, 2004, 12:30:18 AM »
i just started the Hyalgan shots last week...by sounds of what everyone is saying this might be a complete waste of time ??? i hope pain goes away for a little while anyway....but doc had my hopes up that this would give me at least a year break from pain....ooh well thanyou all enjoying reading your opinions.
Wendy
Torn Medial Meniscus & LR 3/3/03, Maquet Procedure 6/11/03, Arthroscopy, medial meniscectomy, revision of Tubercle osteotomy R knee 4/20/04,12/14/04 removal of hardware, 11/03/2006 torn meniscus left knee

Offline grannynan

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Re: Hyalgan
« Reply #13 on: September 19, 2004, 02:52:59 AM »
Hey, Wendy!
Don't give up too soon.  Hylagan and Synvisc definitely didn't work for me, but they work very well for some people.  I know someone whose knee felt "like new" after his injections.  He was supposed to go back after 7 months to have them redone, but said that his knee still felt great - and he has a very active job.  Good luck!
Nancy.

Offline Janet

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Re: Hyalgan
« Reply #14 on: September 19, 2004, 11:40:59 PM »
Wendy:

My OS told me that Synvisc only works about 40% of the time, but for those it helps, it's a miracle. It does seem to work better for early problems than more advanced. The great thing is that the treatment can be repeated as needed....even every six months. I figure it is worth a try and plan to start it in Novmeber.

Janet
Torn quad tendon repair & VMO advancement 4/99, MUA with LOA 10/99, Patella baja and arthrofibrosis, LR & medial release & LOA 5/01, LOA & chondroplasty 6/03,TKR on 11/06, MUA 12/06. From perfect knees to a TKR in 7 years, all from a fall on a wet floor...and early undiagnosed scar tissue.

Offline Mitidai

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Re: Hyalgan
« Reply #15 on: September 23, 2004, 07:33:19 AM »
I completed my synvisc injections August 25th and I'm still waiting for results.  My oa is pretty advanced.  I'm still waiting to hear if I'm a candidate for a new oa brace that's out too.   Doesn't seem to be much  help for those of us who they say "You're too young".  That's when you want to be active but can't because your knees hurt.  It's getting pretty discouraging.   ???

JAN
9-2002 medial menisectomy left knee
11-2003 lateral menisectomy and microfracture left knee
11-2003 fractured cartilage left knee
lateral menisectomy right knee 1-2005
microfracture right knee 1-2005
tkr left knee 1-2006
arthroscopy and lateral femoral chondroplasty 9-2006

Offline wend1175

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Re: Hyalgan
« Reply #16 on: September 23, 2004, 02:57:36 PM »
Thankyou all for your responsed i am very discouraged at this point hope these injections work for me...after 3 surgeries on my knee and the Arthritis is so bad they cant do the Cartilage regrowth that they where going too...they told me there is not enough cartilage to work with anymore.....now i get to look forward the the left knee being done if the Hyalgan works on the right knee
sorry im venting just discouraging i havent been to work in over a year because in constant pain....Just hope this works
Wendy
Torn Medial Meniscus & LR 3/3/03, Maquet Procedure 6/11/03, Arthroscopy, medial meniscectomy, revision of Tubercle osteotomy R knee 4/20/04,12/14/04 removal of hardware, 11/03/2006 torn meniscus left knee

Offline Abbie s Mom

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Re: Hyalgan
« Reply #17 on: September 23, 2004, 04:11:48 PM »
I get the "too young" also. I am 29 with a 22 month old.
Jennifer Reilly
Abigael's mom 12/4/02
** No problems prior to fall of 12/7/03 on black ice. Is this related??? hmmmm....
Current diagnosis:
Bilateral Femoral-Patella Chrondo
PFS
Mal-tracking

Offline grannynan

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Re: Hyalgan
« Reply #18 on: September 23, 2004, 05:21:56 PM »
Hey, Wendy!
Don't worry about venting.  This is the place to do it.  It's really nice to have someplace to go where you can say whatever you are feeling without feeling guilty. :)
Nancy.

Offline wend1175

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Re: Hyalgan
« Reply #19 on: September 23, 2004, 06:31:49 PM »
Thankyou Nancy, and i also get the your too young for this im 37....
Torn Medial Meniscus & LR 3/3/03, Maquet Procedure 6/11/03, Arthroscopy, medial meniscectomy, revision of Tubercle osteotomy R knee 4/20/04,12/14/04 removal of hardware, 11/03/2006 torn meniscus left knee

Offline Mitidai

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Re: Hyalgan
« Reply #20 on: September 28, 2004, 06:15:57 AM »
Hi Nancy,

I got measured for my knee brace.  The guy who measured me at the os office said it's actually been around for years it's just been improved so it's more comfortable.  He showed me what the brace looks like and it's big and clumsy looking.  Not sure what I'll think about wearing one.  I get it in two weeks.  I still haven't decided if the synvisc worked.  My knee seems to go a few days really good then it's pain as usual.  Before the shot I hardly ever had any pain free days.  Now my other knee has been giving way (buckling) more and that is really worrying me.  I hope I don't have to have that scoped next.

JAN
9-2002 medial menisectomy left knee
11-2003 lateral menisectomy and microfracture left knee
11-2003 fractured cartilage left knee
lateral menisectomy right knee 1-2005
microfracture right knee 1-2005
tkr left knee 1-2006
arthroscopy and lateral femoral chondroplasty 9-2006

Offline wend1175

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Re: Hyalgan
« Reply #21 on: September 28, 2004, 04:04:11 PM »
Well had my second injection still feel no difference in my knee how long does it take if your going to feel a difference ??? My left knee the doc told me 6 weeks after last injection he will start looking into that knee....i feel like i cant win been out of work for over year already and still in pain cant do anything....
wendy
Torn Medial Meniscus & LR 3/3/03, Maquet Procedure 6/11/03, Arthroscopy, medial meniscectomy, revision of Tubercle osteotomy R knee 4/20/04,12/14/04 removal of hardware, 11/03/2006 torn meniscus left knee

Offline seegalone

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Re: Hyalgan
« Reply #22 on: September 28, 2004, 08:26:05 PM »
Hi, Wendy,

I was on this Forum last winter, asking similar questions...
Don't despair, I had 3 injections last Feb-Mar, and about a couple of weeks after last injection I started feeling some relief from pain, which continued to improve, and lasted about 4 mos. I had days when I forgot I had any problem with my knee. This was against all odds: advanced medial OS - bone on bone, with constant pain while walking.  However the honeymoon did not last even 6 mos...  Slowly but surely, within the 5th mos the pain came back  in full force. I had 3 more shots  (Synvisc) finalized about 4 weeks ago. It's much better than it was before the injections, but not as good as the first time. On top of that I had 2 bad reactions (first time just one, and not as severe), and I am still puzzled while this happens. My knee was very swollen with a hard bulge above the knee. I barely could walk for four days.
My last injection, however was almost totally trouble free (just like 2 out of 3 the first time) - just a bit of swelling, tightness, etc, which lasted a couple of days, but did not interfere much with my activities. Is it possible that the site of injection makes a difference, with some of this stuff getting into the tissue surrounding the cavity? In a way it does not make sense; if a long needle can go a fair distance without any "obstacles" on the way, it must be within the cavity. I know that 2 out of 3 shots, which resulted in a lot of swelling, the Os hit the bone, which caused a shooting short lived pain, but an other time it was a clean shot... I am still searching for answers...

I don't know if this "oil change" every 4-5 mos can go on forever, or I should expect less effect with time. It would make some sense as the knee is perhaps deteriorating further, however Synvisc should prevent it...

So, be a bit patient and have hope! The alternatives are not very charming..

Krys ;)

Offline wend1175

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Re: Hyalgan
« Reply #23 on: September 29, 2004, 02:05:17 AM »
Hi Krys
thankyou for letting me know how it is working for you....hope it does do same for me ??? just totally discouraged with everything...no carilage left and a spot inside about the size of quarter they were going to try and regrow the cartilage to cover spot but not enough to work with and its to big to try and fix....gotta love these bad knee's....i will keep you posted and please do the same for me.
thanks again
Wendy
Torn Medial Meniscus & LR 3/3/03, Maquet Procedure 6/11/03, Arthroscopy, medial meniscectomy, revision of Tubercle osteotomy R knee 4/20/04,12/14/04 removal of hardware, 11/03/2006 torn meniscus left knee

Offline Abbie s Mom

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Re: Hyalgan
« Reply #24 on: September 29, 2004, 02:42:41 AM »
Let me know about the regrowing cartilage. I am going to ask my doc about it when I go for the scope.

Jenn
29 mom of Abbie, 22 months
Jennifer Reilly
Abigael's mom 12/4/02
** No problems prior to fall of 12/7/03 on black ice. Is this related??? hmmmm....
Current diagnosis:
Bilateral Femoral-Patella Chrondo
PFS
Mal-tracking

Offline seegalone

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Re: Hyalgan
« Reply #25 on: September 29, 2004, 05:19:05 AM »
Hi again, Jenn,

Just my 2 cents. The cartilage re-growth is called Carticel. There must be a thread here somewhere. It's apparently most suitable for younger people like yourself. I'm too far gone in age and knee condition. It's worth checking into it. My OS showed me a picture of a gal about 37, who got back to athletic life after about one year of tratment, having barely been able to walk before.

Good luck,

Krys

Offline Abbie s Mom

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Re: Hyalgan
« Reply #26 on: September 29, 2004, 02:45:36 PM »
Thanks!

It's put a real strain on my marriage. Sean is turning 40 when I turn 30, and all he does is make fun that he can move better than me etc... My friends always want to go out and go shopping, I have to be wheeled.

Jenn :(
Jennifer Reilly
Abigael's mom 12/4/02
** No problems prior to fall of 12/7/03 on black ice. Is this related??? hmmmm....
Current diagnosis:
Bilateral Femoral-Patella Chrondo
PFS
Mal-tracking

Offline seegalone

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Re: Hyalgan
« Reply #27 on: September 29, 2004, 07:10:36 PM »
Jenn,
The glass is either half empty or half full... I think you are very lucky to have someone to wheel you, and a little kid to cheer you up! Your condition is not going to last forever. Some others might have to struggle with this whole thing on their own, and the kids in college don't seem to give a diddly hoot, at this point in their life, about their mothers struggle.  Not that they do not love her, they are not "into it"... So cheer up !!!
Krys

Offline wend1175

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Re: Hyalgan
« Reply #28 on: September 29, 2004, 07:12:18 PM »
Also with Carticel the procedure take about a year to finish and first 4 month you would be on crutches with no weight bearing on the leg...so it is a lot to conisider
Torn Medial Meniscus & LR 3/3/03, Maquet Procedure 6/11/03, Arthroscopy, medial meniscectomy, revision of Tubercle osteotomy R knee 4/20/04,12/14/04 removal of hardware, 11/03/2006 torn meniscus left knee

Offline ALyn

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Re: Hyalgan
« Reply #29 on: February 25, 2005, 02:39:22 AM »
Jenn,

How is your knee now - since the allergic reaction to the shot?  Did the doctor do or suggest any type of treatment specifically for the allergic reaction? 

My rhumatologist wants to give me Synvisc, but I am skeptical like many other people, especially after reading so much negative feedback   :-\

Offline Frogfan

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Re: Hyalgan
« Reply #30 on: March 14, 2005, 05:04:16 AM »
Read my post about Hyalgan...so far I think i may be getting a bit of relief as I have not had to take as much pain meds...

good luck
8-27-04 OATS Procedure
2-05 1st injection Hyalgan Injections
2-05 2nd injection of Hyalgan
3-14-05 3rd Injection of Hyalgan

Offline vicki

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Re: Hyalgan
« Reply #31 on: March 15, 2005, 04:15:37 AM »
Krys:   Hi, if I understand your post correctly you are looking for an orthopedic surgeon in the chicago area.   I live in the northwest chicago suburb of Arlington Heights and have a phenomenal surgeon.   He operated on both my shoulders and is not doing work on my knee.   If you are interested, I would gladly forward you his name and phone number.   

In general, I hear Rush Medical Center has an OUTSTANDING orthopedic center.   I am going to do research about their practice.   I understand they are pioneering the key-hole TKR procedure.   Since I'm headed that way I am interested in finding info on the less invasive procedure.   

Anyway, good luck finding your doc.   Let me know if I can be any help.

Vicki
Palatine, IL
[email protected]