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Offline Heather M.

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Article on RA advances
« on: September 14, 2003, 10:33:11 PM »
I found this article featuring a prestigious medical award for two doctors who have truly advanced the study of treatments for RA.  

Also, Christopher Reeve (Superman) received recognition for the work he has done for victims of spinal chord injuries.

For those who have RA, this clinic in England sounds like it is offering some hope of treatments that slow the damage.

Scientists, Reeve win top awards

Malcolm Ritter
Associated Press
Sept. 14, 2003 12:00 AM

NEW YORK - Actor Christopher Reeve, two scientists who discovered an arthritis therapy and a researcher who helped show how cells read their genes have won prestigious medical awards.

The prizes, from the Albert and Mary Lasker Foundation, will be awarded Friday in New York. In the last 11 years, 15 scientists who received one have gone on to win a Nobel Prize.

Reeve, 50, will receive the Lasker public service award for "perceptive, sustained and heroic advocacy" for medical research and for disabled people.

Best known for playing Superman in movies, Reeve took on a new role after he was paralyzed from the shoulders down in a 1995 accident. He now chairs the board of the Christopher Reeve Paralysis Foundation, which finances research on spinal cord injury and other disorders of the central nervous system. It also seeks to improve quality of life for people with disabilities.

Armed with star power and a sophisticated knowledge of medical research, Reeve has lobbied federal and state lawmakers on that topic while pursuing both a rigorous rehabilitation program and a career in acting and directing, the foundation said.

"He has demonstrated great courage in a truly bleak situation, finding a way to exert tremendous power even though his body has lost much of its vigor," the board said. "He . . . has transformed himself from one type of Superman into another."

The two other Lasker awards include a $50,000 honorarium.

The prize for clinical medical research will be shared by two scientists who developed a treatment for rheumatoid arthritis and other "autoimmune" diseases in which the body's immune system attacks normal tissue.

The winners are Marc Feldmann and Sir Ravinder N. Maini of the Kennedy Institute of Rheumatology at Imperial College London. They found evidence that a chemical messenger of the immune system, called tumor necrosis factor or TNF, provoked the inflammation that marks rheumatoid arthritis.

They discovered that blocking TNF's effects reduced swelling and destruction of joints in mice with arthritislike symptoms, and in 1992 they performed the first study in humans of anti-TNF therapy for rheumatoid arthritis. The drug relieved symptoms within hours.

The approach is now the basis for several rheumatoid arthritis medicines, which have benefited about 400,000 people with that disease.

The Lasker award for basic medical research will be presented to biochemist Robert Roeder of the Rockefeller University in New York. Starting in the late 1960s, he pioneered studies of how cells in humans and other animals "read" their genes to make proteins. All cells in a person's body carry the same DNA, but they perform different jobs, working as brain cells rather than skin cells, for example, by reading different sets of genes.
Scope #1: LR, part. menisectomy w/cyst, chondroplasty
#2-#5: Lysis of adhesions/scar tissue, AIR, patellar tendon debridement, infections, MUA, insufflation
#6: IT band release / Z-Plasty, synovectomy, LOA/AIR, chondroplasty
2006 Arthrofibrosis, patella baja