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Author Topic: Any downside to Synvisc  (Read 3174 times)

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Offline jmcreynolds

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Any downside to Synvisc
« on: January 09, 2006, 02:56:26 PM »
What, if any, is the downside to synvisc injections?  Does it weaken the cartilage in any way.  I want to try them but want to be fully informed. 
Scope 10/04 and debridement of chondral defect,  OATs on 1/05

Offline speer03

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Re: Any downside to Synvisc
« Reply #1 on: September 25, 2006, 05:33:00 AM »
The downside is that there is a side effect of severe pseudosepsis - basically painful inflamation of the knee.  It is extremely painful and occurs in around 5% of the population in the first series, and then it jumps to 24.6% in the second series. This is widely known and is why they have been losing market share for 5 straight years.  This is also documented in about 12-13 articles in bigtime medical journals, as well as in their own literature.  The next time you get an injection ask to see the paperwork in the box, it's printed right there.

The main difference in Synvisc vs Supartz is that Synvisc is 20% synthetic.   

Supartz is the purest form of hyaluron available today with more active ingredient.  It is also about half price and in over 155 million injections there has never been one reported / documented case of severe pseudosepsis.

Offline Jo-knee

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Re: Any downside to Synvisc
« Reply #2 on: September 25, 2006, 05:46:17 AM »
Wow.
Gotta love that ice!  10/05 lat menisectomy, microfracture to 2 medial femoral defects.