KNEEtalk

The OSTEOARTHRITIS DEPARTMENT => KNEE ARTHRITIS - Injections into the joint => Topic started by: jmcreynolds on January 09, 2006, 02:56:26 PM

Title: Any downside to Synvisc
Post by: jmcreynolds on January 09, 2006, 02:56:26 PM
What, if any, is the downside to synvisc injections?  Does it weaken the cartilage in any way.  I want to try them but want to be fully informed. 
Title: Re: Any downside to Synvisc
Post by: speer03 on September 25, 2006, 05:33:00 AM
The downside is that there is a side effect of severe pseudosepsis - basically painful inflamation of the knee.  It is extremely painful and occurs in around 5% of the population in the first series, and then it jumps to 24.6% in the second series. This is widely known and is why they have been losing market share for 5 straight years.  This is also documented in about 12-13 articles in bigtime medical journals, as well as in their own literature.  The next time you get an injection ask to see the paperwork in the box, it's printed right there.

The main difference in Synvisc vs Supartz is that Synvisc is 20% synthetic.   

Supartz is the purest form of hyaluron available today with more active ingredient.  It is also about half price and in over 155 million injections there has never been one reported / documented case of severe pseudosepsis.
Title: Re: Any downside to Synvisc
Post by: Jo-knee on September 25, 2006, 05:46:17 AM
Wow.