Regenerative orthopaedics implies that damaged tissues within orthopaedics are encouraged to regenerate rather than using foreign materials to replace them.
The developing world of regenerative orthopaedics
Although many of the interventions of regenerative orthopaedics have been around for a decade or two, it is only recently that the concept has been firmly recognised and the discipline clearly differentiated into regenerative medicine and regenerative surgery. The former implies the injection of regenerative materials into tissues and joints, while the latter involves surgical implantation of scaffolds and cells in addition to other regenerative materials such as growth factors.
Advances in Regenerative Orthopaedics. Evans CH. Mayo Clin Proc. 2013 Nov; 88(11): 1323–1339.
Human Adipose Tissue Is a Source of Multipotent Stem Cells. Zuk PA, Zhu M, Ashjian P, De Ugarte DA, Huang JI, Mizuno H, Alfonso ZC, Fraser JK, Benhaim P and Hedrick MH. Mol Biol Cell. 2002 Dec; 13(12): 4279–4295.
Orthopaedic regenerative tissue engineering en route to the holy grail: disequilibrium between the demand and the supply in the operating room. Cengiz IF, Pereira H, de Girolamo L, Cucchiarini M, Espregueira-Mendes J, Reis RL and Oliveira JM. J Exp Orthop. 2018 Dec; 5: 14.
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A simple video explanation of what constitutes regenerative orthopaedics, and how it differs from regenerative medicine.