PE is an abbreviation of 'pulmonary embolus'.
A PE is a blood clot that has become caught in the lungs, usually deriving from a locus in the lower leg (deep vein thrombosis or DVT), perhaps from trauma there. The clots may be multiple and tiny with a predominant symptom of breathlessness, while a massive clot may lead to sudden death. In the lower limb the calf is often swollen.
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Imaging of acute pulmonary embolism: an update. Moore AJE, Wachsmann J, Chamarthy MR, Panjikaran L, Tanabe Y and Rajiah P. Cardiovasc Diagn Ther. 2018 Jun; 8(3): 225–243.