Matrix-induced Autologous Chondrocyte Implant

Matrix-induced autologous chondrocyte implantation - or MACI - is a technique of cartilage repair involving growing cells on a matrix.

chondrocyte harvest
A tiny bit of healthy cartilage is harvested from a non-weight-bearing part of the joint, and sent for culture.

 

Technique of MACI

The technique uses the patient's own cells, which are multiplied in a laboratory, 'seeded' onto a membrane and shipped back to the surgeon for the second stage of the process when the membrane is implanted into the defect in the knee.

 

Synonyms: 
MACI
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CLINICAL PUBLICATIONS

Matrix-induced autologous chondrocyte implantation (MACI) in the knee. Enea D, Cecconi S, Busilacchi A, Manzotti S, Gesuita R and Gigante A. Knee Surg Sports Traumatol Arthrosc. 2012 May;20(5):862-9. doi: 10.1007/s00167-011-1639-1. Epub 2011 Aug 12.

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