Matrix-induced autologous chondrocyte implantation - or MACI - is a technique of cartilage repair involving growing cells on a matrix.
Technique of MACI
The technique uses the patient's own cells, which are multiplied in a laboratory, 'seeded' onto a membrane and shipped back to the surgeon for the second stage of the process when the membrane is implanted into the defect in the knee.
Matrix-induced autologous chondrocyte implantation (MACI) in the knee. Enea D, Cecconi S, Busilacchi A, Manzotti S, Gesuita R and Gigante A. Knee Surg Sports Traumatol Arthrosc. 2012 May;20(5):862-9. doi: 10.1007/s00167-011-1639-1. Epub 2011 Aug 12.