A compartment of the knee is an area of articulation - the knee joint cavity is deemed to have three 'compartments'.

The three compartments of the knee
The three compartments of the knee are:
- the contact area between the femur and tibia bones on the inner (medial) side (medial compartment),
- the contact area between the femur and tibia bones on the outer (lateral) side (lateral compartment),
- the contact area between the patella (kneecap) and the femur bones (patellofemoral compartment).
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CLINICAL PUBLICATIONS
Unloader Braces for Medial Compartment Knee Osteoarthritis - Implications on Mediating Progression. Ramsey DK, and Russell ME. Sports Health. 2009 Sep; 1(5): 416–426.