Biological scaffolds are derived via tissue engineering from matrix materials that normally support the cells of various tissues of the body.
Requirements of biological scaffolds
Biological scaffolds need to be:
- have relevant mechanical properties
- have suitable architecture
- be cost effective to manufacture
Main groups of biomaterials suitable for scaffolds
- synthetic polymers
- natural polymers
Biomaterials & scaffolds for tissue engineering. O'Brien FJ. Materials Today, Volume 14, Issue 3, March 2011, Pages 88-95.
Scaffold Translation: Barriers Between Concept and Clinic. Hollister SJ and Murphy WL. Tissue Eng Part B Rev. 2011 Dec; 17(6): 459–474.