Biological scaffolds are derived via tissue engineering from matrix materials that normally support the cells of various tissues of the body.


Requirements of biological scaffolds

Biological scaffolds need to be:

  • biocompatible
  • biodegradable
  • have relevant mechanical properties
  • have suitable architecture
  • be cost effective to manufacture


Main groups of biomaterials suitable for scaffolds

These include:

  • ceramics
  • synthetic polymers
  • natural polymers

A discussion of newer concepts in fat-derived stem cell work.



Biomaterials & scaffolds for tissue engineering. O'Brien FJ. Materials Today, Volume 14, Issue 3, March 2011, Pages 88-95.

Scaffold Translation: Barriers Between Concept and Clinic. Hollister SJ and Murphy WL. Tissue Eng Part B Rev. 2011 Dec; 17(6): 459–474.

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