Mags, the biggest thing is if you had Left tkr or Right tkr. With automatic, and left tkr there is no real reason not to be able to drive. The instructions I received said may drive when feel ready, and meds don't interfere. I had left tkr and was driving by one week.Did not have a real choice, as I am the mother of 5 and take care of everybody else. There was nobody to drive me around, I went to the store on day 6 and drove myself. Won't say it didn't knock me for aloop, and cause alot of pain, but it had to be done, and nobody else volunteered.SO off to the store. Thank goodness I had LEfT side tkr. NEXT is the right, so it might not work as well. I don't have good flexion and that was my dream with this tkr. THAT And being rid of all the swelling.Neither has happened. At 6 weeks, you should be able to drive depending on the amount of meds and leg and if it is the right leg, you can extend and flex it. Good luck, CALL AND ASK> TEresa