My doc does Denovo and ACI. I had ACI, but Denovo was not presented as an option to me. After the fact, I asked if he even did it for patella and he does. Tried to probe a bit because I was curious why it wasn't presented as an option, but I didn't push too much. I was told by one of his PA's prior to my ACI surgery, but after my cells were already being expanded by Genzyme, that there wasn't sufficient research yet to fully support it's use in PF joint...yet he has done them in the PF joint. Apparently, the Denovo patients are all doing really well at this point though. There aren't longer term studies though to know how it compares vs ACI...like at 5 year point. ACI isn't true hyaline cartilage either though and has fibrocartilage in it also. When it comes time to do my right knee, I'll need to decide if it ask for Denovo or stick with ACI. If get a favorable result, why would I change...but I hear Denovo people seem to recover quicker. I'm actually faring quite well fo 8 weeks out though if I do say so myself.