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Author Topic: 6 Months post-op from autologous stem cell teatment with Dr. Nathan Wei  (Read 2505 times)

Offline sparky52

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I am now 6 months post op from an autologous stem cell injection for chonral defect with Dr. Nathan Wei. I had the proceedure june 18, 2010. It was a single aspiration of stem cells mixed into a prp and fat cocktail and reinjected into my knee using ultrasound for guidance. I followed all rehab instruction including sustained period of non weight bearing and subsequent limited weight bearing. I am a healthy non smoker vegetarian.
I went back to my regular orthopod Dr. Andrew Bishop and he took an x ray of the knee using same machine in same stance ie.apples to apples. There is no visible change in the x-ray from an xray that is 12 months pre- stem cell implant proceedure by Dr. Wei.
However, let me be very clear here. The knee does feel significantly better with no stiffness or pain when I sit.
I am very disappointed not to see any change in the xrays. Dr. Wei feels that growth can occur after 6 months but I am dubious if I cannot see any in first 6 months.
My conclusion is that the proceedure helped with my pain. I cannot say if this is psychosomatic or not.
At this point I may try Regennexx and couple it with arp wave which I just recently met a very satisifed user of. Thought all of you would want to know.
If that doesn't work, then osteotomy.
The game plan keeps evolving.

Offline poke

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Re: 6 Months post-op from autologous stem cell teatment with Dr. Nathan Wei
« Reply #1 on: January 06, 2011, 09:50:56 PM »
Hi Sparky,
 X rays at 6\12 are not likely to show change especially if you have advanced disease. I would take heart from the +ve response you have had and maybe try anothe 2x stem cells with PRP and then take a look at an MRI 1 year down the track... forget the x rays. :)

Offline men-at-arms

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Just read this thread through and thought I chime in with my limited understanding from own research. I was told by two MSC treatment providers to expect regeneration up to 1 year possibly 1.5 years. But dependent on the provider, the total number of cells injected varied. So for me, if the number of stems injected was relatively low, something like 50 million, that more injections are necessary and this raised the cost of course. From Dr. Centeno's website and data he has provided, seems the imagery of regeneration of cartilage have all been via MRI, as MRI probably provides a lot more details than X-ray. The concerns that you have post-procedure were bullet point question marks in my own research notes. I took a very un-bias approach to evaluating MSC injections, other regenerative approaches with and w/o stems cells even though I am very interested in these advance techniques in order to avoid TKR. So, for me -- the input from certain OS's I spoken to did called into question exactly this issue -- how much regeneration if at all, and their opinions did lead me to hold off seriously considering getting MSC injections immediately, and lead me to try simpler and lower cost PRP injections instead. And in my case -- I basically have realized the same level of painless-ness as you with PRP alone. This is not to discourage you, as all those stems cells you received are without doubt in your defective areas and are at work doing certain levels of repair for you. So, may be keep us posted at 1 year and perhaps by then you would have realized detectable amount of cartilage regeneration, especially if image was taken via MRI instead of X-Ray. Best of luck to you~!

Offline dwarren254

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I am about to have the Stem cell with the PRP.
Xrays do not show my cartalage defect you can only see it on my MRI.

DW

Offline Dizzy

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I would tend to agree with what everyone here is saying, an xray probably isn't really the right way to determine the impact, probably need an MRI to do make a determination.

But what really matters is how your knee feels and if it feels better than I would call it a success!
4/10 running overuse injury/PFS diagnosis
6/10, 9/10, 1/11 PT
12/10 Euflexxa
12/10, 2/11, 7/11 Stem cell injections
5/11 to date - ART