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Author Topic: Reaction to second round of Synvisc?  (Read 2954 times)

Offline SmplySweet1021

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Reaction to second round of Synvisc?
« on: November 24, 2010, 09:41:11 PM »
Has anyone else ever had a reaction to Synvisc on their 1st injection of the 2nd round?

I had my first inj yesterday, left the office & was sore nothing bad. By the end of the day it was VERY painful to straighten my leg or bend my knee. The only position that was comfortable was keeping my knee at about 30 degrees bent. When walking I need to keep it slightly bent, and not put my full weight on it....so I look like an idiot limping around.

Called my doc and they said this sometimes happens to patients that are starting their 2nd round of injections. I am on a Depo 6 day pack to help me out, especially since it is a holiday season.

Has anyone else had this problem? How long did it last for you?

Thanks!!
2005 - Blown PCL & LCL due to Riding Accident, Surgery to repair
2006 - New Surgeon due to Problems
2007 Scope & 2 non dissolving screws still in knee
Supartz, Synvisc, Cortisone injections- Didn't Work :-(
Grade 3 Osteoarthritis at 24 yrs old

Offline SmplySweet1021

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Re: Reaction to second round of Synvisc?
« Reply #1 on: November 27, 2010, 09:30:57 PM »
Alright guess I am the only one this happened to.....
2005 - Blown PCL & LCL due to Riding Accident, Surgery to repair
2006 - New Surgeon due to Problems
2007 Scope & 2 non dissolving screws still in knee
Supartz, Synvisc, Cortisone injections- Didn't Work :-(
Grade 3 Osteoarthritis at 24 yrs old

Offline skierboy

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Re: Reaction to second round of Synvisc?
« Reply #2 on: August 29, 2011, 05:37:41 PM »
SmplySweet--

No, you are not alone with this problem.  I have been taking Synvisc injections for the past two years or so, every six months.  No problems, and they helped greatly in terms of lubricating the joint.  Several weeks ago when I had the first of a new series of injections, I had to take a few aspirin that evening to sleep comfortably.  The knees had swollen a bit.  Last Thursday I got follow-on injections in both my knees, and by that evening I could barely walk.  I thought for awhile that I would be awake with the aching pain (particularly in my arthritic left knee) all night, but a couple of Aleve pills got me through the night.  I found, however, that I could only really sleep on my stomach.  For some reason keeping the knee caps pressed onto the bed really reduced the throbbing in the joint.

It is now the following Monday, and I can still barely walk around.  There is clearly a lot on inflammation in each knee joint, esp. the left one.  It is a different kind of inflammation than that caused by arthritis itself, but the net effect is much the same.

It appears that one can have no problem with Synvisc and then have an allergic reaction to the avian elements of the stuff come on months or years later when getting later injections.  What a shame.  I had taken Orthovisc originally and then switched to Synvisc since I did not think I would have any problems with avian products.  That was true at the time -- but it ain't any longer!

Needless to say, I am not going to get any more of these Synvisc injections.  I only hope that I can return back to Orthovisc or an equivalent artificial hyaluronic acid product each six months to help keep my knees lubricated and w/o any adverse reaction to the injections.

What a bummer!
Nov 04 -- LK debridement
Sep 08 -- LK microfracture
May 11 -- RK meniscus trim
Sep 11 -- LK TissueGene-C injection

Offline maryannv

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Re: Reaction to second round of Synvisc?
« Reply #3 on: December 13, 2011, 09:52:41 PM »
ok you wrote this in August. How long did it take to recover? I began my second round on friday, it is now tuesday and i can barely walk. The first round worked like a dream. I almost forgot that I had a problem, and decided to begin the second round in an attempt to maintain.
let me know

Offline marco4432

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Re: Reaction to second round of Synvisc?
« Reply #4 on: December 17, 2011, 06:41:00 PM »
Sorry for your pain


I had two rounds of Synvisc injectios after artoscopic surgerys, both times only 7-10 days of pain reief, Docs Billed Insurance companys every time I went in for injections Medication 800-900 Insurance picked up 85% of cost then Docs charged 25 dollars co pay for every injection, injections not even done by doc just nurse assistant , Docs love money just wish they could show some concern to patient
R Knee Arthospic  06/01/2010, partial lateral menisectomy synvisc injections
Start of dibilitating pain after operation
Ri knee Arthosopic Meniscus tear 03/13/11
partial lateral menisectomy synvisc
 Nerve Surgery09/15/2011Right knee
12/23/11 CT scan nerve block
02/29/12 2nd failed nerve surgery

Offline skierboy

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Re: Reaction to second round of Synvisc?
« Reply #5 on: June 13, 2012, 10:06:57 PM »
I just finished a series of three injections of Euflexxa to relubricate my left knee.  Not a moment's pain or discomfort afterwards.  What a difference to the weeks of stiffness and agony I developed when I got Synvisc injections about a year ago (see my earlier posts in this chain).
Nov 04 -- LK debridement
Sep 08 -- LK microfracture
May 11 -- RK meniscus trim
Sep 11 -- LK TissueGene-C injection