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Author Topic: Regenexx injections - Stem Cells  (Read 141800 times)

Offline rob8647932

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Regenexx injections - Stem Cells
« on: December 16, 2007, 06:23:45 PM »
Does anyone know anything about the newly patented injections of Regenexx. It says it is a mixture of bone marrow stem cells (taken from your hip) and blood from your vein. This mixture is then injected into your knee. Clinical trials have resulted in ~ 30% cartilage regrowth. Not bad.
Left knee - 1997 debridement, 1999 trochlea paste graft / microfracture), 2002 IAGH injections, 2005 plica and synovium removal, 2009 Regenexx injections
Right knee - 1997 debridement, 2000 trochlea paste graft, 2004 IAGH injections, 2008 Regenexx injections

Offline mccartjt

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Re: Regenexx injections - Stem Cells
« Reply #1 on: July 01, 2008, 12:33:07 AM »
I have been wondering the same thing..  Sounds great if it works? Has anyone on this list heard or had any involvement with the folks in Colorado?

Offline believev

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Re: Regenexx injections - Stem Cells
« Reply #2 on: July 01, 2008, 05:40:58 PM »
I tried to call the company but can't get anyone to answer, or call me back.

I'm a little supicious of that.  I want to ask my knee doc about it.

I wish we can find someone who tried it.


Offline Kaputt_Knee

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Re: Regenexx injections - Stem Cells
« Reply #3 on: July 01, 2008, 05:55:49 PM »
There is work being done actively by Dr Jürgen Toft at the Alpha Klinik in Munich. If you google their web site you can read a little about it. He is very pro-active in maintaining a biological solution for as long as possible.

I am hoping to get the permission of my health insurance to be evaluated by him to see if I am a suitable candidate. Anything that will postpone the TKR for as long as possible.

http://www.alphaklinik.de/en/toft/news/Stem_Cell_therapy

Sue  ;) in Germany
1989 big trauma R. knee - sorted
1990-2004 3ACL recons and 20+ arthroscopies -RK
3/06 LK ACL torn!
4/06 ACL recon, kneecap broken
09 &10/06- 2x meniscus trims
3/07 - Notch Plastic & Lateral Release
14/8/08 complete revision ACL plus LCL/PLC recon
6/2/09 returned to skiing! Whoopee

Offline Saverio

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Re: Regenexx injections - Stem Cells
« Reply #4 on: August 20, 2008, 09:37:49 PM »
I had the regenexx procedure done on my left knee in March '08.  I am 57 yo, with bone on bone in both knees.  I have had 4 operations (2 in each knee) since 1996.  I have gone to the best OS's in USA and they all said let me know when you want TKRs done.  I love playing tennis and wish to ski again.  I had scheduled 2 TKRs in Jan '08.  Just before Xmas '07 I saw a news clip of regenexx on TV.  I looked them up and researched them.  I thought what do I have to loose.  It's my own stem cells and it's only injections.  I cancelled my TKR's and went to Denver.  After 1 month my left knee started to respond to PT.  It got stronger almost every week.  I could feel the quads were not atrifing.  I am now playing more singles.  I am scheduled for the treatment on my right knee in September.  Hope to be skiing this winter.


Offline rob8647932

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Re: Regenexx injections - Stem Cells
« Reply #5 on: August 25, 2008, 03:52:04 PM »
Savario,

How many injectons did you have and how long did it take to feel better? Did you have any restrictions.

Thanks
Left knee - 1997 debridement, 1999 trochlea paste graft / microfracture), 2002 IAGH injections, 2005 plica and synovium removal, 2009 Regenexx injections
Right knee - 1997 debridement, 2000 trochlea paste graft, 2004 IAGH injections, 2008 Regenexx injections

Offline loua

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Re: Regenexx injections - Stem Cells
« Reply #6 on: August 25, 2008, 05:42:33 PM »
I filled out the online form and got a response back within a few hours.  I have emailed back & forth with them several times.  They are supposed to open an office in Fla. soon.

Offline 60schld

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Re: Regenexx injections - Stem Cells
« Reply #7 on: August 27, 2008, 11:52:47 PM »
Saverio,  Please give us all the details. :D   I am dying to find out all I can.  :) ;D
Thanks!!
TKR  finally done!!!  9/9/13     Whew!!

Offline darlp

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Re: Regenexx injections - Stem Cells
« Reply #8 on: September 03, 2008, 11:50:17 AM »
Here's the response I got:

In response to your email, Dr. Centeno and his associates are having good success in treating patients with OA/DJD of the knees as well as degenerative disk disease, with loss of cartilage, with our non surgical procedure.  The best method for them to give you their feedback to whether you could benefit from Regenexx is to review your most recent MRIs or x-rays.  If you would be interested, we would be happy to do this. 

Our website www.regenexx.com has the most updated information regarding the procedure along with Dr. Centeno’s latest publications.  Regenexx is currently only available at our Denver location although we plan to open in Florida later in the year.  The procedure involves drawing our patient’s blood and bone marrow, growing their stem cells in our laboratory for approximately 3 weeks and then injecting the stem cells into the affected joint.  Patients come to Denver for an overnight stay for their blood and bone marrow draw and then for up to 9 days for a series of injections to place the stem cells.  This timeframe is dependent on the course of therapy prescribed to address your particular issues.

Please let me know what additional questions you may have or how I may assist you.

Thank you for your interest.

All the best!

Kelly Fulton, RN
Regenerative Sciences
Unleash the power of your stem cells


Offline 60schld

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Re: Regenexx injections - Stem Cells
« Reply #9 on: September 08, 2008, 10:43:10 PM »
To darlp- I ermailed them also and the reply was identical.  I guess it's their form letter.  Still,
I'd much prefer hearing from someone who actually did it?!  Let's hope we have some people
out there who have tried it.  Best Wishes :) :D 8)
TKR  finally done!!!  9/9/13     Whew!!

Offline mccartjt

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Re: Regenexx injections - Stem Cells
« Reply #10 on: September 12, 2008, 05:00:28 PM »
Have any of you folks read this press release from Dr Joe Maroon Neuro Surgeon to the Pittsburg Steelers?

http://www.pittsburghlive.com/x/pittsburghtrib/s_578202.html

There are overachievers, and then there is Dr. Joe Maroon.

Three or four days a week, he swims an hour at Sewickley YMCA, beginning at 5:15 a.m., before heading to his job as vice chairman of the department of neurological surgery at University of Pittsburgh Medical Center. He'll operate, see patients or both, and then he'll bike or jog for about an hour.

Every weekend, Maroon does his own version of a triathlon, swimming one to two miles, biking 50 to 75 miles and running between eight and 15 miles in one day. Last weekend, it was a 1.5-mile swim, 75-mile ride and 12-mile run.

"The problem is I have to double that for Hawaii," Maroon said.

Maroon, who is the Steelers' neurosurgeon, is in training for the Ford Ironman World Championship in Kona, Hawaii, this October.

The race consists of a 2.4-mile open-ocean swim, 112 miles of biking and 26.2 miles of running.

Maroon is 67 years old and will be 68 at the time of the race.

A year ago, Maroon's colleagues were telling him his racing career was over.

The trouble started five years ago, when the Sewickley resident was competing in his fifth Ironman race and injured his left knee. He continued to race, but his last major competition was in 2005, when he finished in sixth place in his age group in the triathlon at the Senior Olympics, held in Pittsburgh.

Last year, Maroon was told by two orthopedic surgeons that he was going to need a knee replacement.

That was unacceptable.

"They told me if I had an artificial knee, I'd never run again," Maroon said. "I could walk, but I'd never run again."

Maroon started researching on the Internet and found Dr. Christopher Centeno and his Colorado-based company, Regenerative Services. Centeno developed a procedure called Regenexx, in which he extracts stem cells from a patient's own bone marrow, cultivates them, then injects them into the affected area to regenerate bone and cartilage.

Eight months ago, Maroon got the first of two injections into his left knee, and last weekend he completed a half-Ironman distance race in Muncie, Ind. He finished fifth in his age group and qualified for the Ironman World Championship in the process.

The procedure, which costs $5,000 to $7,000, is not covered by insurance. Maroon knows of no one in the Pittsburgh area doing similar work.

Centeno said that while his typical patient is active and between 40 and 60 years old, Maroon will be the first to go on to compete in an Ironman.

"I kid Joe that I think he's the biggest overachiever that I know," Centeno said. "We're thankful he did well."

This will be Maroon's third trip to Kona.

"I started 20 years ago doing triathlons," he said. "Each year I just increased the bar, just like I do with my training now. That's the remarkable thing about it; you see what your body can do and adjust to."



Karen Price can be reached at kprice@tribweb.com or 412-320-7980.
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Offline 60schld

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Re: Regenexx injections - Stem Cells
« Reply #11 on: September 12, 2008, 10:25:50 PM »
Hi, I have read this and everything else I could find.  Somehow I just need to hear more from
more ordinary folks?!  You can never be sure it's not a media, advertisement. ??? ::) Hope
someone else is able to report. ??? :) 8)
TKR  finally done!!!  9/9/13     Whew!!

Offline mayme

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Re: Regenexx injections - Stem Cells
« Reply #12 on: September 13, 2008, 12:31:43 AM »
I'm like you 60schld, I'm incredibly intrigued by what I'm reading about Regennex but would sure love to hear from some "real" folks.

I have to tell you though, I am mightily impressed that one of their success stories is the vice chairman of the Pittsburg neurological surgery dept. Not too shabby.

Offline plantgeek58

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Re: Regenexx injections - Stem Cells
« Reply #13 on: September 13, 2008, 05:16:03 PM »
I decided to look up Dr. Centeno's company after reading this post and ran across something that very much disturbs me. The FDA recently sent his company a notification that he is in violation of their regulations and that they may seek legal action against him if he doesn't comply. As a Biotechnology student, I had to learn all about the processes by which new medicines and treatments get approved, and it appears that Dr. Centeno has simply decided to bypass all of this and simply bring his treatment to market without FDA approval.

This product is considered a new drug because it is used to treat human disease. There are testimonials to that right on his website. As such, the product is subject to FDA regulation, but Dr. Centeno has not gone through the proper procedures to get FDA approval. He has not filed an Investigational New Drug Application, nor has he gotten an approved Biologics License. Do we even know if there have been any clinical trials conducted? Without these, how are we to know about any potential side effects and how often they may occur?

 FDA regulations were put into place to safeguard the public against false claims or untested and potentially harmful medicines. I am highly suspicious of anyone who isn't willing to go through the proper channels to get his/her product approved. It can be a long, drawn out process that takes years to complete, but the fact that it is so thorough means that in the end, you can be sure of having a product that is truly effective without being harmful. As much as I would like to believe in this product, I would urge everyone considering it to use extreme caution.

There is one other consideration also. If the product doesn't get FDA approval, insurance companies will never cover the procedure and patients will continue to have to pay out of pocket for it. Anyone considering the treatment should ask the company whether they will still be charged if the harvested cells fail to grow in the lab. My OS has stated that that sometimes happens with cells grown for ACI, but patients are still responsible for the full fee.

Here is the link to the FDA letter, if anyone wants to read it:
http://www.fda.gov/CBER/compl/regen072508.htm
Terre
RK 7/04 part. m. menisc., plica resect., MF
    3/05 part. m. menisc., open OATS
    1/07 part l. menisc., MF, patellar chondroplasty
    9/08 MF
LK 11/04 & 8/06 part m. menisc.
     7/07 LR, patellar tendon debrid., part m. menisc.

Offline 60schld

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Re: Regenexx injections - Stem Cells
« Reply #14 on: September 13, 2008, 09:06:39 PM »
Hi plantgeek58
             Thank you soooo much for that info.  It's just the type of thing I've been looking for
and how do we know that Dr.Maroon and Dr. Centeno are not in business together?  Nobody
has actually seen Dr. Maroon's medical records?? We're all just believing everything because
we are seeking miracles.  Still, maybe someday it will be a really viable, workable treatment. ???
                       Hopeful, yet very cautious :o :D
                                                                  60schld
TKR  finally done!!!  9/9/13     Whew!!