For what it's worth, I used to take celebrex and thought it wasn't really doing much. Then I went off it and wow, it was helping the pain a lot. Since I am 62, I'm afraid to take it now because it may be associated with heart problems which run in my family, but that's another story. In the U.S., vioxx and bextra have been taken off the market for the heart problems but celebrex remains available, so I guess there is less risk there.Nancy