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An overview of the status quo in knee osteotomy (part 1b of a course on realignment osteotomy)

One of the problems with knee osteotomy is that it had a bad reputation in the past.

It used to be an operation very commonly performed in the UK, where it was done as the only surgical alternative to knee replacement. In fact it was the predecessor to knee replacement surgery, so before we had knee replacements all we could do was osteotomies.

The procedure was very crude – you took an osteotome (chisel), you took out a wedge of bone from the outside of the tibia, move the leg over and initially nothing was used to hold the new position other than plaster. Later on, metal plates or staples were used to secure the bone in the new position, but these were not strong enough to permit early walking. Patients were therefore put in plaster and told not to walk for six weeks, and even though the bone usually healed, patients did not go on to have good knee function. So the original popularity of the procedure gradually declined. In my training I always wanted to do knee surgery and even though I worked for some top knee surgeons, I only saw two or three osteotomies in six years of my registrar training.

Dr (mr) adrian wilson

Then I went to Australia for 12 months to do a fellowship in knee surgery at the Brisbane Orthopaedic Sports Medicine Centre. Here they had re-discovered these procedures and they had moved forward in terms of the sophistication of planning surgery and fixing the osteotomies, so now I was seeing an osteotomy every other week!

The osteotomy world opened up to me further when I then went to visit a group of knee surgeons in Nijnmegen in Holland. I discovered that in Europe over the last ten years the operation has been revolutionised, and it had changed completely from being a very basic procedure - where the realignment calculations were quite crude and the bone fixation was relatively weak requiring patients to be kept in plaster - to a very well designed procedure. Presently, osteotomy surgery uses a very sophisticated computer system to plan exactly where to make the cut and how much bone to remove ( in the case of a closing wedge procedure), or how much to open the newly made gap in the cut bone (in the case of an opening wedge osteotomy). This calculation is accurate to a millimetre and to a degree of correction.

These more sophisticated techniques enable the surgeon to carry out meticulous pre-operative planning. The patient has a series of long-leg X-rays and these are then entered into a computer system that works out the angles of the hip, the knee and the ankle. Then by looking at the computer images, the surgeon can plan exactly where he wants to put the weight-bearing line (which I discuss later in this course), and that computer programme then gives him a figure which he takes to the operating theatre. Here, using an image intensifier - which is a type of X-ray machine - wires are placed at the appropriate position across the tibia or the femur. Then the tibia or femur is realigned to exactly the right degree to the nearest millimetre or half-millimetre.

TOMOfix plate

The next big revolutionary event in osteotomy has been the development of knee plates, and this has come through from the Swiss surgeons and their trauma work. Around ten years ago Dr Alex Staubli invented a new locking plate called the TOMOfix plate, currently manufactured by Synthes. This is truly a revolutionary plate because it not only holds the osteotomy rock solid but in 95% of cases it holds it so well that patients can weight bear immediately without any plaster and without a knee brace. Obviously for the first few weeks we advise that they do very little to allow the wound to heal (simple exercises only and pottering about on their crutches), but they can safely walk from day one because this plate is so strong. That again has revolutionised the rehabilitation after this operation because the patients are weight bearing immediately, they are moving their knees immediately and you know if things go well after a straight forward osteotomy you can be walking back to work doing a desk-based job at 6 weeks having had this pretty major operation. As the knee is allowed to move freely there are no real problems with stiffness post-operatively.

The way the TOMOfix is designed is that you have three screws at the top that lock into the top of the tibia, and then you have four screws below the osteotomy and finally you have one important screw that virtually sits in the osteotomy or preferably just above it. And for people under 60kg Synthes have developed a small low profile form of TOMOfix (specifically aimed at the Far Eastern market). The PEEK Plate by Arthrex is based on this, and is much smaller plate with fewer screws (see the box on the right below).

The double screw-hole is based around the idea of a locking plate. Before, our plates for fixing fractures just had simple screw holes and they were eccentric, meaning you could position the screw slightly differently and by doing so make the bones move apart needlessly.

In this photo the screws are all locked in. You can see the osteotomy site quite clearly. The very first screw below the osteotomy site you sometimes need to move into the non-locking position to actually pull the shin back onto the plate again to reduce it perfectly.

 

Arthrex are really interested in the whole idea of osteotomy, and they with Giancarlo Puddu (an Italian Professor) popularised the whole of the opening wedge technique about 10 years ago with the Puddu plate, named after Professor Puddu who invented it. Professor Puddu is very imaginative and he developed this plate that was great at the time. You made your cut, you opened it, you put your plate on, you usually filled it with something to hope that it would fill in with bone, but it wasn’t something you could weight-bear on so the patients had to keep off it for at least six weeks. One of the problems was that there was a relatively high incidence of failure with the plate breaking, so they’re good, and if you have got a compliant patient they work quite well for small corrections, but for big corrections it is not a very robust plate and they do break.

TOMOfix by Synthes was the next generation of osteotomy plate and the inventors actually looked at Puddu’s plate and compared them both in laboratory testing, looking at what they are like when you compress them and when you twist them, and TOMOfix came out on top based on this idea of a plate that enhances fracture healing and is also very strong so that you can walk on it, and it encourages the bone to heal.

Now Arthrex have looked at the TOMOfix and thought ‘What can we do to better this?”

They have come up with this what they call the PEEK Powerplate, which they are about to launch and go live with towards the end of 2010. You pick it up and say “Is this a sort of template?” - it looks like a trial product, not the real thing. This is because it looks just like the TOMOfix but it weighs virtually nothing because it is made of carbon fibre and it has a very low profile, so the chances are that patients are not going to get irritation from the plate. And if it is as strong as it says it is on the box – on loading it both pressing down on it axially and twisting it and trying to get the thing to break they say that it is superior in strength to TOMOfix and its biomechanical properties are superior. They haven’t developed one for the femur yet – there is going to be a family of them, I think. I am going to go to Munich in a few weeks’ time to have a go on a cadaver with one and I made some suggestions to them with regards to the design. They thought about a lot of things but they have missed one or two of the tricks that the Swiss and the Dutch and the Germans have thought about, and they haven’t really dealt with that in their plate. So we are going to look at it in their lab with a few of their technicians. So I am going to fly over.

I also mentioned to them that no-one has got a device yet where you can dial in the exact amount of slope correction you want during your osteotomy. So you cut the bone from the side and it would be relatively straight-forward to fix it from the front above the level of the osteotomy and below and then actually physically dial in the slope. So we are going to look at that as well. (I discuss 'slope' later on in the section on osteotomy for ligament problems).

If you put one screw in at one edge and you place another screw at the other side of the fracture eccentrically, by tightening the screw the plate and screw can pull the bone in a certain direction. You can just move it very very slightly to actually close up a fracture and compress it. So basically we had these simple holes that were slightly eccentric so that you could alter the position of the screw within it slightly, but basically it was just a hole. And the TOMOfix is a locking plate so the screw actually locks into the plate itself. Each screw hole can be used for both locking and for non-locking.

So if you want to reduce a fracture and actually get the fracture fragments to move towards the plate, you have the non-locking option, so you just use a single screw. But if you really want to get a rigid fixation you use the locking option. It has that option at every single hole, so you can use the one or the other. We tend to lock all of them but there is a very clever trick that we use in the first hole below the osteotomy site – basically when you make the osteotomy you aim to sort of bring your cut not quite the full way across – so if you are doing it from the medial side you go almost all the way across and you stop approximately 5 mm short of the lateral cortex, and by doing that you create this hinge point. You don’t want to break through though.

Previously, if you broke through the other side of the bone (lateral cortex), that was a major complication and tricky to make right. The osteotomy construct would fall apart and the bone fragments would lose their position. With the new TOMOfix plate we can actually reduce the bone back onto the plate by using what we call ‘the golden screw’, which is a non locking screw. We can place this screw into the first hole below the osteotomy and we substitute it later in the operation. So if during the operation we break through the other side of the tibia (lateral cortex) and the tibia slips slightly, that can be relatively easily fixed by using a reducing screw to move the tibia back into the ideal position. That is the main purpose of the non-locking holes in the plate. All we have to do at the end is change that non-locking screw for a locking screw.

Once the osteotomy has been opened to our set level, the laminar spreaders are used to maintain that position and the plate is placed on the tibia. Once the ideal osteotomy gap is achieved the plate is safely secured with locking screws above and below the osteotomy, the laminar spreaders are removed and the wound is closed.

I need to mention that knee osteotomy is not a popular operation in the USA. I think it is an historical thing. The knee surgeons in the States that specialise in soft tissue/ligament surgery do perform osteotomies but for very different reasons. In the UK, osteotomy surgery is usually performed to relieve the pressure in knees with localised arthritis. In the States,  it is carried out as an adjunct to ligament reconstruction, in patients who present where the outer side/lateral knee ligaments have failed, usually in association with a posterior cruciate ligament (PCL) injury. Those patients have bowed knees (varus malalignment, much like the patients with medial compartment arthritis) and when they walk their leg clearly thrusts outwards at the knee because the stabilising lateral ligaments have failed. In these patients who have a combination of ligament deficiency and bony mal-alignment you have to address both issues otherwise the operation might not work. If you carry out the osteotomy first as part of a combined procedure, which is what we try and do, you change the alignment of the leg - you put them into valgus, which takes the tension off the lateral side of the knee and then your lateral reconstruction is highly likely to work. So although they do carry out osteotomies in the States it is not as common an operation as in some other parts of the world. It tends to be done there more for knee instability rather than knee pain.

Updated: 02 May, 2013
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